Behavior of a Synthesized Bone Cement in Simulated Body Fluid

In this research, effect of soaking time of a new synthesized hydroxyapatite-based bone cement in simulated body fluid (SBF) on the final phase and strength has been studied. The powder section of the cement has been synthesized by using tricalcium phosphate, calcium carbonate and anhydrous dicalcium phosphate. The liquid phase of the cement consists of different concentrations of NaH2PO4.2H2O. Soaking the prepared cement in SBF solution for appropriate time resulted in transformation of the composition of the cement into hydroxyapatite and hence the strength of the cement has been increased. The results have shown that by increasing the concentration of liquid phase, the compressive strength of the cement has decreased. The highest strength of cements was obtained at 37±2.5 MPa, with the liquid concentration of 1%, after 14 days of soaking in SBF solution. It seems that the synthesized cement can be used as a bone graft in orthopedic surgeries.